Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
Atomic Force Microscopy01:08

Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
Scanning Electron Microscopy01:07

Scanning Electron Microscopy

A scanning electron microscope (SEM) is used to study the surface features of a sample by using an electron beam that scans the sample surface in a two-dimensional manner. Typically, areas between ~1 centimeter to 5 micrometers in width can be imaged. SEM can be used to image bacteria, viruses, tissues as well as larger samples like insects. Conventional SEM gives a magnification ranging from 20X to 30,000X and spatial resolution of 50 to 100 nanometers.
Fundamental Principles
Accelerated...
Transmission Electron Microscopy01:15

Transmission Electron Microscopy

In 1931, physicist Ernst Ruska—building on the idea that magnetic fields can direct an electron beam just as lenses can direct a beam of light in an optical microscope—developed the first prototype of the electron microscope. This development led to the development of the field of electron microscopy. In the transmission electron microscope (TEM), electrons are produced by a hot tungsten element and accelerated by a potential difference in an electron gun, which gives them up to 400 keV in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A quantum ruler for orbital magnetism in moiré quantum matter.

Science (New York, N.Y.)·2023
Same author

Bistability in atomic-scale antiferromagnets.

Science (New York, N.Y.)·2012
Same author

Measurement of fast electron spin relaxation times with atomic resolution.

Science (New York, N.Y.)·2010
Same author

Scattering and interference in epitaxial graphene.

Science (New York, N.Y.)·2007
Same author

Electronic effects in the length distribution of atom chains.

Physical review letters·2006
Same author

Single-atom spin-flip spectroscopy.

Science (New York, N.Y.)·2004

Related Experiment Video

Updated: Jul 12, 2026

All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics
11:33

All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics

Published on: January 19, 2018

Atomic and molecular manipulation with the scanning tunneling microscope.

J A Stroscio, D M Eigler

    Science (New York, N.Y.)
    |November 29, 1991
    PubMed
    Summary

    Scientists can now precisely place individual atoms using scanning tunneling microscopy. This atomic manipulation opens new possibilities for building custom nanostructures and advancing scientific tools.

    Area of Science:

    • Nanotechnology
    • Surface Science
    • Atomic Physics

    Background:

    • The manipulation of matter at the atomic scale has been a long-standing scientific aspiration.
    • Technological advancements are crucial for realizing the potential of atomic-scale engineering.

    Purpose of the Study:

    • To explore the capabilities of atomic and molecular manipulation.
    • To discuss the applications of these techniques in scientific research.

    Main Methods:

    • Utilizing scanning tunneling microscopy (STM) for atomic placement.
    • Leveraging interactions within the STM tunnel junction for manipulation.

    Main Results:

    • Demonstration of precise single-atom placement.

    More Related Videos

    Hand Controlled Manipulation of Single Molecules via a Scanning Probe Microscope with a 3D Virtual Reality Interface
    11:00

    Hand Controlled Manipulation of Single Molecules via a Scanning Probe Microscope with a 3D Virtual Reality Interface

    Published on: October 2, 2016

    Visualizing Uniaxial-strain Manipulation of Antiferromagnetic Domains in Fe1+YTe Using a Spin-polarized Scanning Tunneling Microscope
    09:06

    Visualizing Uniaxial-strain Manipulation of Antiferromagnetic Domains in Fe1+YTe Using a Spin-polarized Scanning Tunneling Microscope

    Published on: March 24, 2019

    Related Experiment Videos

    Last Updated: Jul 12, 2026

    All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics
    11:33

    All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics

    Published on: January 19, 2018

    Hand Controlled Manipulation of Single Molecules via a Scanning Probe Microscope with a 3D Virtual Reality Interface
    11:00

    Hand Controlled Manipulation of Single Molecules via a Scanning Probe Microscope with a 3D Virtual Reality Interface

    Published on: October 2, 2016

    Visualizing Uniaxial-strain Manipulation of Antiferromagnetic Domains in Fe1+YTe Using a Spin-polarized Scanning Tunneling Microscope
    09:06

    Visualizing Uniaxial-strain Manipulation of Antiferromagnetic Domains in Fe1+YTe Using a Spin-polarized Scanning Tunneling Microscope

    Published on: March 24, 2019

  • Construction of atom-by-atom structures according to specific designs.

    • Conclusions:

    • Atomic manipulation is now a reality due to advances in STM.
    • This capability offers significant potential as a tool for scientific discovery and technological innovation.