Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Oropharyngeal and esophageal function in scleroderma.

A Montesi1, A Pesaresi, M L Cavalli

  • 1Servizio di Radiologia, Ospedale Regionale Umberto 1st, Ancona, Italy.

Dysphagia
|January 1, 1991
PubMed
Summary

Systemic sclerosis (scleroderma) frequently causes swallowing difficulties, with 26% of patients experiencing oropharyngeal issues. These problems correlate with esophageal dysmotility and more severe disease symptoms.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of Fragmentation Functions for Jets Dominated by Light Quarks and Gluons from pp and Pb+Pb Collisions in ATLAS.

Physical review letters·2019
Same author

Combination of Searches for Invisible Higgs Boson Decays with the ATLAS Experiment.

Physical review letters·2019
Same author

Measurement of differential cross-sections of a single top quark produced in association with a <i>W</i> boson at <math> </math> with ATLAS.

The European physical journal. C, Particles and fields·2019
Same author

Search for the direct production of charginos and neutralinos in final states with tau leptons in <math> </math> <i>pp</i> collisions with the ATLAS detector.

The European physical journal. C, Particles and fields·2019
Same author

Measurement of quarkonium production in proton-lead and proton-proton collisions at <math></math> with the ATLAS detector.

The European physical journal. C, Particles and fields·2019
Same author

Measurement of longitudinal flow decorrelations in Pb+Pb collisions at <math> </math> and 5.02 TeV with the ATLAS detector.

The European physical journal. C, Particles and fields·2019

Area of Science:

  • Gastroenterology
  • Neurology
  • Radiology

Background:

  • Systemic sclerosis (scleroderma) is an autoimmune disease affecting connective tissues.
  • Oropharyngeal and esophageal motility disorders are common in systemic sclerosis.
  • Videofluoroscopy is a key diagnostic tool for evaluating swallowing function.

Purpose of the Study:

  • To determine the incidence of oropharyngeal deglutition abnormalities in systemic sclerosis patients.
  • To correlate radiologic patterns of esophageal motility abnormalities with clinical features.
  • To investigate the relationship between swallowing dysfunction and disease severity.

Main Methods:

  • Fifty-one patients with systemic sclerosis underwent videofluoroscopy during barium swallow.
  • Oropharyngeal and esophageal motility were assessed radiologically.

Related Experiment Videos

  • Clinical features, including Raynaud's phenomenon and skin sclerosis, were recorded.

    • Main Results:

    • Twenty-six percent of patients exhibited oropharyngeal swallowing dysfunction.
    • Dysphagia severity correlated with esophageal dysmotility and advanced disease.
    • Esophageal motility abnormalities were present in 80% of patients.
    • Oropharyngeal disorders were linked to a higher incidence of pulmonary disease.

    Conclusions:

    • Oropharyngeal swallowing abnormalities are common in systemic sclerosis and linked to disease severity.
    • Esophageal dysfunction is frequent, particularly in early disease stages.
    • Videofluoroscopy is valuable for identifying and characterizing swallowing deficits in systemic sclerosis.