[Incidence of streptococcal pharyngitis]

A C Peñalba Citores1, B Riaño Méndez, R Marañón Pardillo

  • 1Sección de Urgencias, Hospital Materno-Infantil Gregorio Marañón, Madrid, España. anitapenalba@hotmail.com

Insights

Group A Streptococcus (GAS) pharyngitis is more common in children under two than previously thought, with lower rapid test accuracy and higher erythromycin resistance. Group C Streptococcus was also noted in this age group.

Area of Science:

  • Pediatric Infectious Diseases
  • Microbiology
  • Epidemiology

Context:

  • Acute pharyngitis is common in children, but data on very young children (<2 years) is limited.
  • Group A beta-hemolytic Streptococcus (GAS) is a primary cause of bacterial pharyngitis.
  • Group C Streptococcus is also a potential pathogen in pharyngitis.

Purpose:

  • To determine the incidence of streptococcal pharyngitis in patients younger than 2 years.
  • To evaluate the role of group C streptococci in acute pharyngitis in symptomatic patients.
  • To assess the accuracy of rapid antigen detection tests and antibiotic resistance patterns in this age group.

Summary:

  • Group A beta-hemolytic Streptococcus (GAS) was identified in 12.6% of patients under 2 years old.
  • Rapid antigen detection tests showed lower sensitivity (78%) and PPV (69%) in this young cohort.
  • Higher rates of fever, rash, and catarrhal symptoms were observed in younger children, along with increased erythromycin resistance (24.7%) and a notable presence of Group C Streptococcus (5.2%).

Impact:

  • Findings suggest a higher incidence of GAS pharyngitis in children under 2 than previously reported.
  • Highlights the need for careful interpretation of rapid tests in this age group due to reduced accuracy.
  • Indicates a potential increase in erythromycin resistance and the significance of Group C Streptococcus in pediatric pharyngitis.
Abstract

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