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[Fluid and electrolyte disorders following surgery for brain tumors]
S Segura Matute1, M Balaguer Gargallo, F J Cambra Lasaosa
1Unidad de Cuidados Intensivos Pediátricos, Servicio de Pediatría, Hospital Sant Joan de Déu-Clínic, Universitat de Barcelona, España. ssegura@hsjdbcn.org
Anales De Pediatria (Barcelona, Spain : 2003)
|September 6, 2007
Summary
Postoperative fluid and electrolyte disorders, primarily diabetes insipidus, occur in 15.4% of pediatric CNS tumor surgeries. Early desmopressin treatment for diabetes insipidus is effective, while SWS and SIADH require careful sodium monitoring.
Area of Science:
- Pediatric neurosurgery
- Endocrinology
- Oncology
Context:
- Fluid and electrolyte imbalances are common after pediatric central nervous system (CNS) tumor surgery.
- Conditions like diabetes insipidus, salt wasting syndrome (SWS), and syndrome of inappropriate antidiuretic hormone secretion (SIADH) can impact neurological recovery.
Purpose:
- To determine the incidence and characteristics of postoperative fluid and electrolyte disorders in children undergoing CNS tumor surgery.
- To evaluate the clinical presentation and management of these disorders.
Summary:
- A retrospective analysis of 149 pediatric patients revealed a 15.4% incidence of fluid and electrolyte disorders post-CNS tumor surgery.
- Diabetes insipidus was the most frequent (65.2%), typically resolving within 73 hours with desmopressin, except in cases of hypothalamic-pituitary axis injury.
- Salt wasting syndrome (SWS) occurred in 26.1% and SIADH in two patients, both requiring specific management strategies.
Impact:
- Early diagnosis and prompt treatment of these disorders are crucial for preventing adverse neurological outcomes.
- Understanding the incidence and characteristics aids in optimizing patient care and management protocols in pediatric neuro-oncology.
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