Histamine improves antigen uptake and cross-presentation by dendritic cells

Maria Marta Amaral1, Carlos Davio, Ana Ceballos

  • 1Institute of Hematologic Research, National Academy of Medicine and National Reference Center for AIDS, Department of Microbiology, Buenos Aires University School of Medicine, Buenos Aires, Argentina.

Summary

Histamine enhances dendritic cell (DC) functions like endocytosis and cross-presentation of soluble allergens, potentially impacting allergic responses. This effect depends on the antigen form and specific histamine receptors involved.

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