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Updated: Aug 10, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
Published on: May 31, 2016
Rapid development of extensive macrovascular calcifications in a type I diabetic patient
P B Carroll1, H L Rilo, Y J Zeng
1Department of Medicine and Surgery, University of Pittsburgh, Pennsylvania 15213.
Abstract:
This is a case report of a 35-year-old woman with a 15-year history of type I diabetes mellitus, who developed extensive macrovascular calcifications of the abdominal aorta and all its tributaries within 7 months of developing renal insufficiency. The patient was maintained on hemodialysis and peritoneal dialysis for a total of 3 months, then underwent combined cadaveric renal and pancreatic islet transplantation. Although some vascular calcifications are known to occur in elderly patients and in patients with long-standing uremia, it was the rapidity and extent of development of these lesions in this young woman that is astonishing.
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