Related Experiment Videos
Complications of endorectal pull-through for Hirschsprung's disease
G M Tariq1, R J Brereton, V M Wright
1Hospitals for Sick Children, London, England.
Insights
Endorectal pull-through (ERPT) for Hirschsprung's disease shows mixed long-term outcomes. While many survivors achieve good results, a significant portion experiences issues like diarrhea and incontinence, sometimes requiring further surgery.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Clinical Outcomes Research
Background:
- Hirschsprung's disease is a congenital condition affecting the large intestine.
- Endorectal pull-through (ERPT) is a common surgical approach for this condition.
Purpose of the Study:
- To evaluate the long-term functional outcomes of endorectal pull-through (ERPT) in infants with Hirschsprung's disease.
- To assess the rate of complications and need for revision surgery following ERPT.
Main Methods:
- Retrospective analysis of 57 infants undergoing ERPT over 10 years.
- Assessment of postoperative outcomes including functional results, complications, and reoperations.
Main Results:
- 3 out of 57 patients died postoperatively.
- Of 44 survivors over 3 years, 52% had excellent results; 82% of 28 survivors over 5 years had satisfactory results.
- 18% of survivors experienced diarrhea with incontinence; 9.4% required a Duhamel procedure within 4 years.
Conclusions:
- ERPT offers potentially good long-term outcomes for Hirschsprung's disease, particularly in older children.
- A notable percentage of patients experience persistent functional issues, including incontinence and diarrhea, necessitating careful monitoring and potential reintervention.
Abstract:
In 10 years, 57 infants with Hirschsprung's disease underwent endorectal pull-through (ERPT). Postoperatively, 3 patients died. Of the 44 survivors with an intact endorectal anastomosis aged more than 3 years, 23 (52%) had an excellent result, and of the 28 children more than 5 years old, 23 (82%) had a satisfactory result. Of the 53 known survivors of all ages, 18% suffered from diarrhea with intermittent incontinence and 5 (9.4%) had undergone a Duhamel procedure within 4 years of ERPT.