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Updated: Jul 12, 2026

Gastrointestinal Motility Monitor (GIMM)
08:15

Gastrointestinal Motility Monitor (GIMM)

Published on: December 1, 2010

[Effects of stigma maydis polysaccharide on gastrointestinal movement]

Juan Du1, Qi-tai Xu, Xing-hua Gao

  • 1College of Pharmacy, Henan University, Kaifeng 475001, China.

Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica
|September 7, 2007
PubMed
Abstract

Insights

Stigma maydis polysaccharide (SMPS) enhances gastrointestinal movement in animal models, likely by increasing cholecystokinin (CCK) levels. This suggests SMPS may promote digestive motility.

Area of Science:

  • Pharmacology
  • Gastroenterology
  • Natural Products

Context:

  • Gastrointestinal motility disorders affect millions globally.
  • Polysaccharides from natural sources are increasingly explored for therapeutic potential.
  • Stigma maydis, a traditional herbal medicine component, warrants investigation for its physiological effects.

Purpose:

  • To investigate the impact of stigma maydis polysaccharide (SMPS) on gastrointestinal motility.
  • To elucidate the potential mechanisms underlying SMPS's effects on digestion.

Summary:

  • SMPS significantly increased intestinal movement and stool output in mice.
  • In mice, SMPS affected gastric emptying.
  • In rats, SMPS prolonged gastric emptying time but accelerated intestinal content movement, correlating with increased plasma cholecystokinin (CCK).

Impact:

  • Findings suggest SMPS as a potential agent for managing gastrointestinal motility.
  • The study highlights the role of CCK in mediating the gastrointestinal effects of SMPS.
  • Further research could explore SMPS for conditions like constipation or delayed gastric emptying.

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