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A physical analogy of the genetic toggle switch
1Institute for Biocomplexity and Informatics, University of Calgary, Calgary, Alberta, Canada. mandrecu@ucalgary.ca
Abstract:
We show that there is a physical analogy between a stochastic model of a genetic toggle switch system and a thermostated particle moving in a potential field, derived from the probability distribution of the toggle switch. This result suggests that one can actually simulate the dynamics of a more complex gene network by considering an ensemble of thermostated particles moving in a potential field, derived from the stationary distribution of the chemical stochastic model describing the gene network.
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