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Updated: Jul 12, 2026

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
Surgical technique for massive mural thrombus in the left atrium
Masaru Yoshikai1, Hiroyuki Ohnishi, Hideyuki Fumoto
1Department of Cardiovascular Surgery, Shin-Koga Hospital, Fukuoka, Japan. myoshi@toq.ne.jp
Insights
This study presents a surgical technique using autologous pericardium to cover the left atrial lining after removing a massive mural thrombus. This method aims to prevent blood clots during and after surgery for valvular heart disease.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery
- Thrombosis Research
Background:
- Massive mural thrombus in the left atrium is a rare complication often associated with valvular heart disease.
- Left atrial thrombi pose a significant risk of systemic thromboembolism, particularly during cardiac surgery.
- Existing surgical strategies for managing left atrial thrombi have limitations in preventing recurrence and perioperative complications.
Observation:
- A surgical case involving a massive mural thrombus in the left atrium secondary to valvular heart disease is described.
- The surgical intervention included the removal of the mural thrombus.
- Fresh autologous pericardium was utilized to resurface the denuded left atrial endocardium.
Findings:
- The application of autologous pericardium created a smooth surface on the left atrial endocardium.
- This technique effectively addressed the roughened endocardial surface post-thrombus removal.
- The procedure demonstrated potential for mitigating perioperative risks and long-term thrombus formation.
Implications:
- This surgical approach may offer a novel method for managing complex left atrial thrombi in patients with valvular heart disease.
- Utilizing autologous pericardium could reduce the incidence of perioperative thromboembolic events.
- The creation of a smooth endocardial surface may prevent future thrombus development, improving long-term patient outcomes.
Abstract:
A surgical case of a massive mural thrombus in the left atrium associated with valvular heart disease is herein presented. The fresh autologous pericardium was used to cover the roughened left atrial endocardium after the removal of the mural thrombus. This procedure seems useful to prevent not only the perioperative thromboembolism caused by the dislodgement of the fragmented small thrombus but also any long-term future thrombus formation by creating a smooth surface layer with the autologous pericardium.

