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Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
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A local region of interest image reconstruction via filtered backprojection for fan-beam differential phase-contrast

Zhihua Qi1, Guang-Hong Chen

  • 1Department of Medical Physics, University of Wisconsin in Madison, 600 Highland Avenue, Madison, WI 53792-1590, USA.

Physics in Medicine and Biology
|September 7, 2007
PubMed

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Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
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