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Duration of cardiopulmonary bypass compared with changes in the plasma protease systems
U E Kongsgaard1, N Smith-Erichsen, O Geiran
1Department of Anaesthesiology, Rikshospitalet, Oslo, Norway.
Scandinavian Journal of Thoracic and Cardiovascular Surgery
|January 1, 1991
Abstract:
Forty patients undergoing elective coronary artery bypass grafting were investigated concerning association between duration of cardiopulmonary bypass (CPB) and changes in the plasma protease systems. Spontaneous enzyme activity, proenzymes and functional inhibition capacities in the fibrinolytic, plasma kallikrein-kinin and coagulation systems were measured before, during and after CPB and in the immediate postoperative period. No clear relationship was revealed between changes in the measured variables and the duration of CPB.