Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The Human Genome Project: misguided science policy.

M C Rechsteiner1

  • 1Department of Biochemistry, University of Utah School of Medicine, Salt Lake City 84132.

Trends in Biochemical Sciences
|December 1, 1991
PubMed
Summary

Genome mapping and sequencing projects are criticized as wasteful, prioritizing data over scientific process. This approach may hinder understanding of diseases and training future scientists.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Subcellular localization of proteasomes and their regulatory complexes in mammalian cells.

The Biochemical journal·2000
Same author

Intracellular localization of proteasomal degradation of a viral antigen.

The Journal of cell biology·1999
Same author

Potential immunocompetence of proteolytic fragments produced by proteasomes before evolution of the vertebrate immune system.

The Journal of experimental medicine·1997
Same author

Proposed role of a gamma-interferon inducible proteasome-regulator in antigen presentation.

Advances in experimental medicine and biology·1996
Same author

Circular pancreatic trypsin inhibitor. A novel substrate for studies on intracellular proteolysis.

The Journal of biological chemistry·1989
Same author

Microinjection studies on selective protein degradation: relationships between stability, structure, and location.

Biomedica biochimica acta·1986

Area of Science:

  • Genomics
  • Bioinformatics
  • Scientific Funding

Background:

  • Genome mapping and sequencing projects are major scientific endeavors.
  • These projects aim to determine the complete DNA sequence of organisms.

Purpose of the Study:

  • Critically evaluate the scientific and educational value of large-scale genome projects.
  • Assess the impact of genome projects on research funding and scientific training.

Main Methods:

  • This is a critical review and opinion piece.
  • Analysis of the focus on 'products of science' versus the 'process of science'.

Main Results:

  • Genome projects are considered inappropriate and wasteful expenditures.
  • The acquired nucleotide sequences may offer limited insights into human diseases or fundamental biological processes.
  • The routine nature of sequencing is unsuitable for training young scientists.

Conclusions:

  • Genome sequencing projects may divert essential research funds from universities.
  • These projects could negatively impact the education of future scientific investigators.
  • A shift in focus from data acquisition to the scientific process is suggested.

Related Experiment Videos