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Fractures in multiple sclerosis.

E Stenager1, K Jensen

  • 1Clinical Neuro-Psychiatric Research Unit, Odense University Hospital, Denmark.

Acta Neurologica Belgica
|January 1, 1991
PubMed
Summary
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Fractures are common in multiple sclerosis (MS) patients, particularly after disease onset. Bone health and fracture risk increase with age and MS duration.

Area of Science:

  • Neurology
  • Orthopedics
  • Bone Health

Background:

  • Multiple Sclerosis (MS) is a chronic neurological disease.
  • Fracture risk in MS patients is not well-established.
  • Understanding fracture patterns can inform patient care.

Purpose of the Study:

  • To determine the prevalence and characteristics of fractures in a cohort of MS patients.
  • To explore the relationship between fractures, age, and disease duration in MS.
  • To assess the association between MS and osteoporosis.

Main Methods:

  • Cross-sectional study design.
  • Inclusion of 299 patients with Multiple Sclerosis (MS).
  • Data collection on fracture history, location, and osteoporosis diagnosis.

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Main Results:

  • 22 out of 299 MS patients (7.4%) reported fractures, with 17 occurring after MS onset.
  • Femoral neck and trochanter fractures were most common (41%).
  • Fracture incidence correlated positively with increasing age and disease duration; only 1 patient had osteoporosis.

Conclusions:

  • Fractures are a significant concern in MS patients, increasing with age and disease progression.
  • The low rate of osteoporosis suggests other factors contribute to fracture risk in MS.
  • Further investigation, potentially via a case-control study, is warranted to elucidate causative factors.