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Bioreactors: design and operation.

C L Cooney

    Science (New York, N.Y.)
    |February 11, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Bioreactor design is key for efficient biochemical production. Advances in bioreactor technology require collaboration between biologists and engineers for optimal productivity.

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    Area of Science:

    • Biochemical Engineering
    • Biotechnology
    • Process Engineering

    Background:

    • Bioreactors are crucial for converting feedstock into products.
    • Biocatalysts determine reaction yield and selectivity.
    • Process technology significantly impacts overall productivity.

    Purpose of the Study:

    • To highlight the role of bioreactor design in biochemical processes.
    • To emphasize the interdisciplinary nature of biochemical reaction engineering.
    • To discuss the impact of technological advancements on bioreactor development.

    Main Methods:

    • Review of bioreactor design principles.
    • Analysis of factors influencing reaction yield, selectivity, and productivity.
    • Examination of advancements in immobilization and continuous processing.

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    Main Results:

    • Bioreactor technology is central to linking feedstock and product.
    • Biochemical reaction engineering serves as a bridge between biology and engineering.
    • Developments focus on whole cell immobilization, immobilized enzymes, continuous reaction, and process control.

    Conclusions:

    • Bioreactor design is critical for optimizing biochemical production.
    • Cross-disciplinary interaction is essential for the biochemical process industry.
    • Future developments will increasingly rely on integrated biological and engineering approaches.