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Updated: Feb 17, 2026

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation
Published on: June 13, 2025
[Arterial surgery of the upper limb].
L Perrault1, J Lassonde, F Laurendeau
1Département de Chirurgie, Hôpital Maisonneuve-Rosemont, Montreal, Québec, Canada.
Upper limb arterial surgery effectively treats trauma, acute ischemia, and chronic ischemia, achieving excellent outcomes in most patients. Despite challenges like high mortality in acute cases, overall results demonstrate the procedure
Area of Science:
- Vascular Surgery
- Upper Extremity Revascularization
- Peripheral Arterial Disease
Context:
- Arterial surgery of the upper limb constitutes a small but significant portion of peripheral vascular procedures.
- A retrospective review of 58 procedures in 45 patients from 1976 to 1989.
- Patients were categorized by etiology: trauma, acute non-traumatic ischemia, and chronic ischemia.
Purpose:
- To evaluate the outcomes of surgical interventions for various etiologies of upper limb arterial disease.
- To analyze the efficacy of different surgical techniques including angioplasty, anastomosis, bypass, ligation, and thrombectomy.
- To assess the overall success rates, mortality, and amputation rates associated with these procedures.
Summary:
- 16 patients with arterial trauma (blunt, penetrating, iatrogenic) showed excellent outcomes (93%) with angioplasty, anastomosis, bypass, ligation, or thrombectomy.
- 16 patients with acute non-traumatic ischemia, primarily due to cardiac emboli, had a high mortality (31%) despite thromboembolectomy.
- 13 patients with chronic ischemia, mostly subclavian artery related, achieved good results (78%) with bypass or endarterectomy.
Impact:
- Overall, 90% of surviving patients experienced satisfactory results, with an 11.1% operative mortality and 13% amputation rate.
- The study highlights the effectiveness of arterial reconstruction for upper limb ischemia, while underscoring the risks associated with acute embolic events.
- Findings provide valuable insights into managing upper limb arterial pathologies and optimizing surgical strategies.
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