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[Focus on anticoagulants]
1Service de Cardiologie, Hôpital Pitié-Salpêtrière, Paris.
More and more heparins are available to the prescriber and low molecular weight heparins have brought about a modification of prescribing habits. Some complications linked to the use of heparins remain insufficiently known: thrombocytopenia and acute pulmonary hypertension during neutralization for example. Treatment monitoring must be clearly codified to increase effectiveness and reduce the number of accidents thus achieving a better risk/benefit ratio for such treatment. Some of the Vitamin K antagonists have specific properties which should be known, particularly relating to their half-life. Monitoring is important, it is provided by INR and adapted to the indications. The world of anticoagulants is in flux; the movement must be followed as it may well accelerate with the arrival of new antithrombotic drugs.
More and more heparins are available to the prescriber and low molecular weight heparins have brought about a modification of prescribing habits. Some complications linked to the use of heparins remain insufficiently known: thrombocytopenia and acute pulmonary hypertension during neutralization for example. Treatment monitoring must be clearly codified to increase effectiveness and reduce the number of accidents thus achieving a better risk/benefit ratio for such treatment. Some of the Vitamin K antagonists have specific properties which should be known, particularly relating to their half-life. Monitoring is important, it is provided by INR and adapted to the indications. The world of anticoagulants is in flux; the movement must be followed as it may well accelerate with the arrival of new antithrombotic drugs.