Related Experiment Video
Updated: Aug 9, 2026

Creation of Murine Experimental Abdominal Aortic Aneurysms with Elastase
Published on: July 23, 2009
[Extra-peritoneal operations in arteriosclerotic lesions of the abdominal aorta and its branches]
Insights
The extraperitoneal approach for aorto-femoral reconstructions reduces complications. Postoperative plasmapheresis aids in managing hemorheological and lipoprotein disorders for better atherosclerosis obliterans treatment outcomes.
Area of Science:
- Vascular Surgery
- Cardiovascular Medicine
- Surgical Oncology
Background:
- Atherosclerotic lesions of the aorta, its branches, and limb arteries affect numerous patients.
- Reconstructive surgery is a common treatment modality for advanced peripheral artery disease.
Purpose of the Study:
- To evaluate the outcomes of extraperitoneal versus transperitoneal approaches in aorto-femoral reconstructions.
- To assess the efficacy of postoperative plasmapheresis in managing hemorheological and lipoprotein disorders following vascular surgery.
- To determine the overall effectiveness of a comprehensive treatment strategy for atherosclerosis obliterans.
Main Methods:
- Analysis of surgical and clinical data from 692 patients undergoing treatment for atherosclerotic lesions.
- Comparative assessment of extraperitoneal and transperitoneal approaches for aorto-femoral bypass.
- Evaluation of postoperative plasmapheresis in 21 patients to normalize blood rheology and lipid profiles.
Main Results:
- The extraperitoneal approach demonstrated significant advantages over the transperitoneal approach, avoiding complications such as intestinal paresis, peritonitis, and intra-abdominal bleeding.
- Coronary and cerebral vascular complications were not elevated with the extraperitoneal approach.
- Postoperative plasmapheresis showed promise in normalizing hemorheological and lipoprotein disorders.
- A complex treatment approach improved both immediate and long-term results of reconstructive vascular operations.
Conclusions:
- The extraperitoneal approach is a safer and more effective method for aorto-femoral reconstructions.
- Postoperative plasmapheresis is a valuable adjunct in managing metabolic disturbances after vascular surgery.
- A multidisciplinary approach enhances outcomes for patients with atherosclerosis obliterans.
Abstract:
The study is based on the analysis of the results of examination and operative treatment of 692 patients with atherosclerotic lesions of the aorta, its branches, and the limb arteries. The advantages of the extraperitoneal approach to the aorta over the transperitoneal approach in aorto-femoral reconstructions is proved. Stable postoperative intestinal paresis, peritonitis, intraabdominal bleeding, eventration, and adhesive disease do not occur with this approach. Such operations are not attended by a high incidence of coronary and cerebral vascular complications during and after the operation. The work gives the first appraisal of the results of postoperative plasmapheresis (21 patients) applied for normalization of hemorheological and lipoprotein disorders in different periods after the operation. The suggested complex approach to the treatment of atherosclerosis obliterans facilitates improvement of the immediate and late-term results of reconstructive operations on the vessels.
Related Concept Videos
Thoracic Aorta
Abdominal Aorta
The celiac trunk, a singular artery, divides into the left gastric artery, which...
Peripheral Artery Disease III: Interprofessional Care
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Aneurysm III: Interprofessional Care
Aneurysm IV: Nursing Management

