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Updated: Jul 11, 2026

Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection
Published on: November 3, 2012
Human immunodeficiency virus infection in a child presenting as herpes zoster ophthalmicus
Nidhi Pandey1, A K Chandrakar, S L Adile
1Department of Ophthalmology, Pt JNM Medical College, Raipur 492009.
Insights
A 9-year-old boy with herpes zoster ophthalmicus was diagnosed with human immunodeficiency virus (HIV). Early diagnosis and treatment with acyclovir and antiretroviral therapy led to a favorable response, highlighting HIV in young patients.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Virology
Background:
- Herpes zoster (shingles) is typically seen in older adults.
- Unusual occurrence in children warrants investigation for underlying conditions.
- Human immunodeficiency virus (HIV) infection can manifest with opportunistic infections.
Observation:
- A 9-year-old boy presented with herpes zoster ophthalmicus (shingles affecting the eye).
- He had a history of abdominal surgery and blood transfusion 1.5 years prior.
- Symptoms included malaise, fever, weight loss, and a subsequent blistering rash around the eye.
Findings:
- Investigations revealed the boy was infected with human immunodeficiency virus (HIV).
- Herpes zoster ophthalmicus was an early manifestation of pediatric HIV infection.
- The patient responded well to systemic acyclovir and antiretroviral treatment.
Implications:
- This case underscores the importance of considering HIV in children presenting with atypical infections like herpes zoster.
- Prompt diagnosis and initiation of antiretroviral therapy are crucial for managing HIV and its complications in pediatric patients.
- Ophthalmologists should be vigilant for signs of systemic illness, including HIV, in young patients with herpes zoster ophthalmicus.
Abstract:
Herpes zoster is mainly a disease of the elderly. Its occurrence in younger age should be viewed with suspicion. A 9-year-old boy presented with herpes zoster ophthalmicus. He had a history of abdominal surgery one and half years back during which he had received blood transfusion. A year following the surgery he developed general malaise and fever with progressive weight loss. He was treated by local doctors. Subsequently he developed eruptions of blisters around right eye for a duration of 8 days, with which he presented to the department of ophthalmology, Pt JNM Medical College, Raipur. On investigations he was found to have infected with human immunodeficiency virus. Systemic acyclovir along with antiretroviral treatment was started, to which he showed favourable response.
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