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Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...

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Related Experiment Video

Updated: Jul 11, 2026

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer
06:01

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer

Published on: July 6, 2017

Perianal eccrine adenocarcinoma.

Tsz-Ho Leung1, Henry Hsin-Chung Lee, Shih-Chang Chang

  • 1Section of Colorectal Surgery, Department of Surgery, Cathay General Hospital, Taipei, Taiwan. hhc.lee@gmail.com.

World Journal of Surgical Oncology
|September 8, 2007
PubMed
Summary

Eccrine carcinoma, a rare sweat gland tumor, has a high recurrence rate. Early consideration of this malignancy is crucial for recurrent skin tumors and perianal fistulas.

Area of Science:

  • Oncology
  • Dermatology
  • Surgical Pathology

Background:

  • Eccrine carcinoma is a rare malignant tumor originating from sweat glands.
  • It is characterized by a high recurrence rate after simple excision.
  • Adjuvant therapy often shows limited efficacy, necessitating aggressive surgical approaches.

Purpose of the Study:

  • To report an unusual case of perianal eccrine carcinoma.
  • To highlight the importance of considering eccrine carcinoma in specific clinical scenarios.

Main Methods:

  • Case report of a patient with perianal eccrine carcinoma.
  • Initial presentation mimicked a perianal abscess.

Main Results:

  • The study details an unusual presentation of eccrine carcinoma.

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Last Updated: Jul 11, 2026

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  • Highlights the diagnostic challenge posed by its mimicry of common conditions.
  • Conclusions:

    • Eccrine carcinomas, though rare, should be considered in cases of recurrent skin tumors.
    • Clinicians should maintain a high index of suspicion for eccrine carcinoma in recurrent perianal fistulas.