Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Malaria01:29

Malaria

Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Symbiosis00:58

Symbiosis

Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
Retrovirus Life Cycles01:10

Retrovirus Life Cycles

Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the retrovirus to...
Diversity of Protists II01:27

Diversity of Protists II

Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Protocol for a phase 3, randomized, double-blind clinical trial evaluating the safety and immunogenicity of the MVA-BN® vaccine against mpox in children aged 4 to less than 24 months in the Democratic Republic of the Congo: Data to guide future paediatric vaccination strategies.

Vaccine·2026
Same author

Effects of climate change-related hazards on food security and health within refugee settlements in Uganda.

Conflict and health·2026
Same author

Trends in prevalence and predictors of anemia among school-aged children in Tanzania: analysis of 2019-2023 cross-sectional surveys using a multilevel logistic regression model.

BMC public health·2026
Same author

<i>Plasmodium falciparum</i> Malaria and Arbovirus Co-Exposure in the Boende Health Zone, Northwestern Democratic Republic of the Congo.

Tropical medicine and infectious disease·2026
Same author

Assessment of community knowledge, attitudes, and practices related to schistosomiasis in a hyper-endemic region of the Democratic Republic of Congo: mixed methods.

BMC public health·2026
Same author

Liver and bladder morbidity in a Schistosoma mansoni and haematobium co-endemic area in the Democratic Republic of Congo.

PLoS neglected tropical diseases·2026

Related Experiment Video

Updated: Jul 11, 2026

An In vitro Co-infection Model to Study Plasmodium falciparum-HIV-1 Interactions in Human Primary Monocyte-derived Immune Cells
07:39

An In vitro Co-infection Model to Study Plasmodium falciparum-HIV-1 Interactions in Human Primary Monocyte-derived Immune Cells

Published on: August 15, 2012

Malaria and HIV: a silent alliance.

Jean-Pierre Van geertruyden1, Umberto D'Alessandro

  • 1Department Parasitology, Unit of Epidemiology, Institute of Tropical Medicine, Nationalestraat 155, B-2000 Antwerp, Belgium. jpvangeertruyden@itg.be

Trends in Parasitology
|September 8, 2007
PubMed
Summary

Co-infection with HIV and malaria in sub-Saharan Africa fuels the spread of both diseases. Recurrent malaria can increase HIV prevalence by elevating HIV viral loads.

Area of Science:

  • Epidemiology
  • Mathematical Modeling
  • Infectious Diseases

Background:

  • HIV and malaria are significant causes of illness in sub-Saharan Africa.
  • Understanding the interplay between these co-infections is crucial for public health.

Purpose of the Study:

  • To investigate the synergistic relationship between HIV and malaria co-infection.
  • To quantify the impact of co-infection on the spread and prevalence of both diseases using a mathematical model.

Main Methods:

  • Development and parameterization of a mathematical model incorporating documented interactions between HIV and malaria.
  • Simulation of disease dynamics under various co-infection scenarios.

Main Results:

  • Concomitant HIV and malaria infections accelerate the transmission of both pathogens.

More Related Videos

An In Vitro Model for Measuring Immune Responses to Malaria in the Context of HIV Co-infection
08:14

An In Vitro Model for Measuring Immune Responses to Malaria in the Context of HIV Co-infection

Published on: October 6, 2015

An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei
09:02

An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei

Published on: February 17, 2014

Related Experiment Videos

Last Updated: Jul 11, 2026

An In vitro Co-infection Model to Study Plasmodium falciparum-HIV-1 Interactions in Human Primary Monocyte-derived Immune Cells
07:39

An In vitro Co-infection Model to Study Plasmodium falciparum-HIV-1 Interactions in Human Primary Monocyte-derived Immune Cells

Published on: August 15, 2012

An In Vitro Model for Measuring Immune Responses to Malaria in the Context of HIV Co-infection
08:14

An In Vitro Model for Measuring Immune Responses to Malaria in the Context of HIV Co-infection

Published on: October 6, 2015

An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei
09:02

An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei

Published on: February 17, 2014

  • Recurrent malaria episodes lead to transiently elevated HIV viral loads, potentially increasing overall HIV prevalence.
  • The model suggests the actual impact of this interaction may be underestimated.

    • Conclusions:

    • Co-infection with HIV and malaria presents a significant public health challenge in sub-Saharan Africa.
    • Mathematical modeling highlights the crucial role of recurrent co-infections in driving HIV epidemic dynamics.
    • Interventions targeting both HIV and malaria are essential to mitigate their combined impact.