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Mayaro virus: imported cases of human infection in São Paulo State, Brazil

Terezinha Lisieux M Coimbra1, Cecília L S Santos, Akemi Suzuki

  • 1Seção de Vírus Transmitidos por Artrópodos, Instituto Adolfo Lutz, São Paulo, SP, Brasil. licoimbra@ial.sp.gov.br

Revista Do Instituto De Medicina Tropical De Sao Paulo
|September 8, 2007
PubMed

Insights

Mayaro virus (MAYV) causes febrile illness in Brazil. Laboratory confirmation is crucial as symptoms can mimic dengue, highlighting the need for accurate arbovirus diagnosis.

Area of Science:

  • Arbovirology
  • Medical Entomology
  • Tropical Medicine

Background:

  • Mayaro virus (MAYV), an Alphavirus, circulates in South American forests via wild vertebrates and Haemagogus mosquitoes.
  • MAYV infections typically occur sporadically in individuals with forest exposure.

Observation:

  • Three male cases of MAYV fever were identified in Camapuã, MS, Brazil.
  • Serum analysis showed monotypic seroconversion to MAYV, confirmed by hemagglutination inhibition tests.
  • Virus isolation from blood samples and subsequent identification via cell culture and RT-PCR confirmed MAYV infection.

Findings:

  • Laboratory confirmation is essential for diagnosing MAYV infections.
  • MAYV-induced febrile illness can present with symptoms similar to other arboviruses, such as dengue.
  • This study confirms MAYV circulation and infection in humans in the Camapuã region of Brazil.

Implications:

  • Highlights the importance of diagnostic vigilance for arboviral diseases in endemic areas.
  • Emphasizes the need for differential diagnosis between MAYV and other febrile illnesses like dengue.
  • Underscores the role of laboratory diagnostics in public health surveillance of emerging infectious diseases.

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