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Updated: Jul 11, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
An innovative approach to integrated medicines management
Claire Scullin1, Michael G Scott, Anita Hogg
1Clinical and Practice Research Group, School of Pharmacy, Queen's University Belfast, Belfast, UK.
Integrated medicines management (IMM) services significantly reduced hospital readmissions and length of stay. This comprehensive pharmaceutical care model can be a template for routine services, improving patient outcomes.
Area of Science:
- Clinical Pharmacy
- Health Services Research
- Patient Care Management
Background:
- Medicines management is crucial for patients at risk of drug-related problems.
- Hospital journeys involve multiple stages requiring coordinated pharmaceutical care.
- Existing hospital care models may not fully address comprehensive medication management.
Purpose of the Study:
- To evaluate the impact of integrated medicines management (IMM) services on patient care.
- To assess clinical and economic outcomes associated with enhanced pharmacist input.
- To determine if IMM improves patient care from admission through discharge.
Main Methods:
- A randomized controlled trial comparing IMM service with regular hospital care.
- Patients at risk of drug-related problems were assigned to either IMM or usual care.
- IMM involved comprehensive pharmaceutical care across admission, inpatient, and discharge stages.
Main Results:
- IMM service reduced hospital length of stay by 2 days (P=0.003).
- IMM patients showed a decreased 12-month readmission rate (40.8% vs 49.3%, p=0.027).
- Time to readmission was 20 days longer for IMM patients (P=0.0356), preventing one readmission per 12 patients.
Conclusions:
- Integrated medicines management services are highly effective in improving patient outcomes.
- The IMM model can serve as a template for implementing comprehensive pharmaceutical care routinely.
- The service was positively received by healthcare professionals, indicating potential for wider adoption.
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