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Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations
Published on: January 8, 2013
A guide to modelling cardiac electrical activity in anatomically detailed ventricles
1Department of Computer Science, University of Sheffield, Regent Court, 211 Portobello Street, Sheffield, S1 4DP, UK. r.h.clayton@sheffield.ac.uk
Progress in Biophysics and Molecular Biology
|September 11, 2007
Summary
Researchers are developing detailed heart models for cardiac electrophysiology. This guide offers resources for creating integrative, anatomically accurate ventricular models, integrating various scientific and programming tools.
Area of Science:
- Cardiac electrophysiology
- Computational biology
- Biomedical modeling
Background:
- Integrative, anatomically accurate heart models represent a significant trend in cardiac electrophysiology.
- These models describe cardiac activity across multiple scales, from sub-cellular to whole organ levels.
- Constructing such models requires diverse information from biology, physiology, electrophysiology, numerical mathematics, and computer programming.
Purpose of the Study:
- To survey recent advancements in integrative modeling of cardiac electrical activity in the ventricles.
- To provide a practical guide to available resources and tools for researchers in this field.
Main Methods:
- Literature review of recent developments in integrative cardiac modeling.
- Compilation of essential resources and tools for constructing anatomically accurate ventricular models.
Main Results:
- Identification of key trends and methodologies in integrative cardiac electrophysiology modeling.
- A curated list of resources and tools facilitating the development of complex heart models.
Conclusions:
- Integrative modeling is a rapidly advancing area in cardiac electrophysiology.
- This article serves as a valuable resource for researchers embarking on the creation of detailed cardiac models.
