Implantation and early embryonic development: implications for pregnancy
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Updated: Jul 11, 2026

Establishment of an Embryo Implantation Model In Vitro
Published on: June 21, 2024
Danielle Vitiello1, Pasquale Patrizio
1Yale University Fertility Center, Department of Obstetrics, Gynecology and Reproductive Sciences, New Haven, CT 06511, USA. pasquale.patrizio@yale.edu
Abstract:
Implantation represents the limiting step in governing reproductive outcomes. The process is driven by both embryo and endometrium alike. Minute perturbations in this orchestration lay foundation for pregnancy-associated complications that may manifest throughout the gestational course. Furthermore, placental function dictates many aspects of fetal development inclusive of preeclampsia and intrauterine growth restriction (IUGR). Novel techniques such as Multigate Spectral Doppler Analysis (MSDA) may allow for early detection and diagnosis of potentially deleterious fetal outcomes.
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