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Related Experiment Videos

MRI of left ventricular function.

Frederick H Epstein1

  • 1Departments of Radiology and Biomedical, University of Virginia Health System, Charlottesville, VA 22908, USA. fredepstein@virginia.edu

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
|September 11, 2007
PubMed
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Cardiac magnetic resonance imaging (CMR) offers accurate, noninvasive assessment of left ventricular (LV) function. Advanced techniques provide detailed insights into cardiac mechanics and viability, aiding in diagnosis and prognosis.

Area of Science:

  • Cardiovascular Imaging
  • Medical Diagnostics

Background:

  • Cardiac magnetic resonance imaging (CMR) is the leading noninvasive method for evaluating left ventricular (LV) function.
  • Modern MRI scanners enable high-resolution, ECG-gated cine imaging of LV function within brief breath-holds.

Purpose of the Study:

  • To review the capabilities of CMR in assessing LV function, including qualitative and quantitative analyses.
  • To highlight advanced CMR techniques for evaluating myocardial strain, twist, and torsion.
  • To discuss the clinical applications of CMR in stress testing, viability assessment, and prognosis.

Main Methods:

  • Acquisition of ECG-gated cine images for LV function assessment.
  • Utilizing computer-based software for quantitative analysis of LV volumes, ejection fraction, and mass.

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  • Employing myocardial tagging and advanced variants for regional function analysis.
  • Integration with perfusion imaging and late gadolinium enhancement for comprehensive evaluation.

    • Main Results:

    • CMR provides high-contrast, high-resolution images of LV function.
    • Quantitative analysis yields precise measurements of LV volumes, ejection fraction, and mass.
    • Advanced techniques assess regional myocardial mechanics (strain, twist, torsion).
    • CMR demonstrates accuracy in stress testing, viability assessment, and prognosis for coronary heart disease.

    Conclusions:

    • CMR is a versatile and accurate tool for comprehensive LV function assessment.
    • It offers valuable prognostic information and aids in detecting cardiac dyssynchrony.
    • Combined CMR techniques provide extensive diagnostic information in a single study.