Related Experiment Video
Updated: Jul 11, 2026

A 3-D Visualization Technique for Bone Remodeling in a Suture Expansion Mouse Model
Published on: August 18, 2023
The effect of tissue expansion on skull bones in the paediatric age group from 2 to 7 years
1Faculty of Medicine, Zagazig University, Zagazig, Sharkia, Egypt. mostafaelsaadi@hotmail.com
Insights
Scalp tissue expansion in young children (2-7 years) may cause skull deformation and suture line changes. CT imaging revealed bony alterations after expansion, requiring careful monitoring in pediatric patients.
Area of Science:
- Plastic Surgery
- Pediatric Surgery
- Craniofacial Surgery
Background:
- Tissue expansion is a common technique for reconstructing scalp defects in both adults and children.
- A significant concern with pediatric scalp expansion is the potential for skull deformation.
Purpose of the Study:
- To evaluate the effects of scalp tissue expansion on the developing skull in children aged 2 to 7 years.
- To assess bony changes and suture line alterations following tissue expansion in pediatric patients.
Main Methods:
- The study involved the application of 40 tissue expanders in 32 pediatric patients (ages 2-7 years) across various scalp areas.
- Computed tomography (CT) imaging was utilized to assess the skull before expansion, immediately after expansion, and three months post-expander removal.
Main Results:
- Post-expansion CT scans revealed multiple bony changes in the pediatric skulls.
- Alterations were also observed at the cranial suture lines, indicating an impact on skull development.
Conclusions:
- Scalp tissue expansion in young children can lead to notable bony changes and affect cranial suture lines.
- Close monitoring and further research are warranted to understand the long-term implications of these changes in pediatric skull development.
Abstract:
Tissue expansion has gained wide application in the reconstruction of scalp defects in adults and children. However, the main concern in the use of scalp expansion in the paediatric population has been the risk of skull deformation. This study shows the application of 40 expanders in 32 patients in different skull areas in the paediatric age group from 2 to 7 years. The effect of expansion on the skull was studied by CT imaging (pre-expansion, post-expansion and 3 months after expander extraction). The post-expansion CT showed multiple bony changes as well as changes at suture lines.
More Related Videos
Related Concept Videos
Sutures of the Skull
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Overview of the Skull
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
Cranial Bones: Superior and Posterior View
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
Cranial Bones: Lateral View
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...

