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Microsomal prostaglandin E2 synthase: a safer target than cyclooxygenases?

Leo Timmers1, Gerard Pasterkamp, Dominique P V de Kleijn

  • 1Laboratory of Experimental Cardiology, University Medical Center Utrecht, the Netherlands. l.timmers@umcutrecht.nl

Molecular Interventions
|September 11, 2007
PubMed
Summary

Novel anti-inflammatory drugs targeting microsomal prostaglandin E2 synthase (mPGES-1) may offer reduced gastrointestinal and cardiovascular risks compared to traditional NSAIDs and coxibs.

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