Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Is atheroma a reversible lesion?

G A Gresham

    Atherosclerosis
    |May 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Atherosclerosis regression is possible. Studies show that modifying lipid factors and using treatments can reverse atheroma, particularly in human lesions. This review explores regression mechanisms and evidence.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The Cerebro-ocular-renal Dystrophies: a new variant.

    Archives of disease in childhood·2010
    Same author

    The use of infrared aided photography in identification of sites of bruises after evidence of the bruise is absent to the naked eye.

    Journal of forensic and legal medicine·2010
    Same author

    Waterhouse-Friderichsen syndrome as a result of non-meningococcal infection.

    Journal of clinical pathology·2004
    Same author

    Non-invasive magnetic resonance imaging assessment of myocardial changes and the effects of angiotensin-converting enzyme inhibition in diabetic rats.

    The Journal of physiology·2002
    Same author

    Magnetic resonance imaging analysis of cardiac cycle events in diabetic rats: the effect of angiotensin-converting enzyme inhibition.

    The Journal of physiology·2002
    Same author

    Magnetic resonance imaging analysis of left ventricular function in normal and spontaneously hypertensive rats.

    The Journal of physiology·1998
    Same journal

    Optimized flow cytometry assay for functional characterization of variants of uncertain significance in familial hypercholesterolemia.

    Atherosclerosis·2026
    Same journal

    Causal insights of modifiable cardiovascular risk factors for dementia risk - potential for efficient prevention and improved brain health.

    Atherosclerosis·2026
    Same journal

    Serial OCT-based coronary physiology and plaque composition in vessels with nonobstructive coronary lesions following intensive lipid-lowering therapy: YELLOW III sub-study.

    Atherosclerosis·2026
    Same journal

    Earliest age to detect lifetime cardiometabolic health stratification in children.

    Atherosclerosis·2026
    Same journal

    Sympathetic neurons exacerbate atherosclerosis by modulating macrophage function via the NPY/Y1R axis.

    Atherosclerosis·2026
    Same journal

    Optimizing lipoprotein(a) testing for immediate clinical impact in primary prevention.

    Atherosclerosis·2026
    See all related articles

    Area of Science:

    • Cardiovascular Science
    • Pathology
    • Biomedical Research

    Background:

    • Atherosclerosis is characterized by lipid buildup in arterial walls.
    • Human lesion regression evidence exists from specific population studies.
    • Understanding atherogenic factors is key to exploring regression.

    Purpose of the Study:

    • To review atherogenic factors and their role in atherosclerosis regression.
    • To examine evidence for the regression of human atherosclerotic lesions.
    • To discuss experimental approaches for studying regression.

    Main Methods:

    • Review of human studies, including those on chronic wasting diseases.
    • Analysis of lipid dynamics within arterial walls (entry, exit, effects).
    • Description of animal experiments involving cholesterol manipulation, hyperoxia, and drug treatments.

    Related Experiment Videos

    Main Results:

    • Evidence suggests that human atherosclerotic lesions can regress.
    • Lipid metabolism and transport in the arterial wall are critical factors.
    • Animal models demonstrate successful induction of atheroma regression through various interventions.

    Conclusions:

    • Atherosclerosis regression is achievable under specific conditions.
    • Modulating lipid factors and employing therapeutic interventions can promote regression.
    • Further research into regression mechanisms holds therapeutic potential.