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Primary hyperparathyroidism: presentation and management.
A H al-Salem1, S al-Mohaya, M al-Awami
1Department of Surgery, King Fahd Hospital, University Al-Khobar, Saudi Arabia.
Indian Journal of Medical Sciences
|November 1, 1991
Summary
Primary hyperparathyroidism was diagnosed in 6.7% of 164 hypercalcemic patients, often presenting late with severe complications. Routine serum calcium testing may reveal more cases, including asymptomatic ones.
Area of Science:
- Endocrinology
- Nephrology
- Bone Metabolism
Background:
- Primary hyperparathyroidism (PHPT) is a common endocrine disorder.
- Its presentation and incidence can vary geographically.
- Early diagnosis is crucial for managing complications.
Purpose of the Study:
- To determine the correlation, frequency, and presentation of PHPT in hypercalcemic patients.
- To compare the incidence with international data.
- To highlight the potential impact of routine screening.
Main Methods:
- Retrospective analysis of 164 hypercalcemic patients.
- Diagnostic criteria for PHPT were applied.
- Clinical data on presentation and complications were collected.
Main Results:
- PHPT was diagnosed in 11 patients (6.7%).
- All diagnosed patients presented late with renal and bony complications.
- The observed incidence appears lower than in Western countries.
Conclusions:
- The incidence of PHPT in this cohort is 6.7%, with late presentation common.
- Routine serum calcium estimation is recommended for early detection, especially for asymptomatic cases.
- Further studies are needed to confirm the lower incidence compared to Western populations.