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Aging of silastic peritoneal catheters.
P Poisetti1, G Bergonzi, S Ballocchi
1Renal Unit, General Hospital, Piacenza, Italy.
The International Journal of Artificial Organs
|December 1, 1991
Summary
Long-term use of Tenckhoff catheters in continuous ambulatory peritoneal dialysis (CAPD) can lead to material degradation. Barium sulphate and environmental factors may cause catheter failure, impacting patient survival.
Area of Science:
- Biomaterials Science
- Nephrology
- Medical Device Engineering
Background:
- Peritoneal access device reliability is crucial for patient survival in continuous ambulatory peritoneal dialysis (CAPD).
- Tenckhoff catheters are commonly used for peritoneal access.
- Catheter material degradation can compromise long-term function.
Purpose of the Study:
- To investigate the long-term material degradation of silicone Tenckhoff catheters used in CAPD.
- To identify factors contributing to the failure of peritoneal access devices.
Main Methods:
- Analysis of six Tenckhoff catheters removed after 39-69 months using scanning electron microscopy (SEM) and attenuated total reflectance infrared spectroscopy (ATR).
- Examination of both extracorporeal and intra-abdominal portions of the catheters.
Main Results:
- The extracorporeal portion showed surface oxidation, cracks, and intraluminal silastic degradation.
- The intra-abdominal portion had biofilm but no oxidation.
- Barium sulphate inclusion may contribute to material brittleness.
Conclusions:
- Long-term exposure to environmental factors and potential material interactions (e.g., barium sulphate) can lead to Tenckhoff catheter aging and failure.
- Catheter degradation affects physico-chemical properties and mechanical resistance.
- Understanding these failure mechanisms is vital for improving CAPD patient outcomes.