Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Embryonic Stem Cells00:57

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Embryonic Stem Cells00:58

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Induced Pluripotent Stem Cells01:06

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic cells are...
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimising same day discharge hemithyroidectomy: defining outcomes, unplanned admissions and patient experience.

Annals of the Royal College of Surgeons of England·2025
Same author

Development of a novel Bluetooth Low Energy device for proximity and location monitoring in grazing sheep.

Animal : an international journal of animal bioscience·2024
Same author

Genome-wide association studies of parasite resistance, productivity and immunology traits in Scottish Blackface sheep.

Animal : an international journal of animal bioscience·2024
Same author

Thyroid lobectomy for low-risk thyroid cancers.

Annals of the Royal College of Surgeons of England·2022
Same author

Metastatic seminoma with isolated gastric metastases: a case report.

Scottish medical journal·2019
Same author

New mastitis phenotypes suitable for genomic selection in meat sheep and their genetic relationships with udder conformation and lamb live weights.

Animal : an international journal of animal bioscience·2018

Related Experiment Video

Updated: Jul 11, 2026

Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats
09:31

Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats

Published on: March 30, 2018

Stem cells: golden opportunities with ethical baggage.

A McLaren

    Science (New York, N.Y.)
    |September 11, 2007
    PubMed
    Summary

    Embryonic stem cells can transform into any cell type, offering potential for organ repair. However, their origin from human embryos presents significant ethical challenges.

    Area of Science:

    • Biomedical research
    • Developmental biology
    • Regenerative medicine

    Background:

    • Embryonic stem cells (ESCs) possess pluripotency, enabling differentiation into diverse cell lineages.
    • The potential therapeutic applications of ESCs include regenerative medicine and tissue repair.
    • Current research explores ESCs for treating diseases affecting various organs.

    Purpose of the Study:

    • To explore the potential of embryonic stem cells for therapeutic tissue generation.
    • To address the ethical considerations associated with the use of human embryonic stem cells.

    Main Methods:

    • Review of current stem cell research and therapeutic strategies.
    • Analysis of ethical frameworks concerning human embryonic stem cell derivation and utilization.

    More Related Videos

    Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy
    10:16

    Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy

    Published on: January 25, 2019

    Isolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta
    07:06

    Isolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta

    Published on: April 3, 2017

    Related Experiment Videos

    Last Updated: Jul 11, 2026

    Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats
    09:31

    Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats

    Published on: March 30, 2018

    Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy
    10:16

    Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy

    Published on: January 25, 2019

    Isolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta
    07:06

    Isolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta

    Published on: April 3, 2017

  • Discussion of alternative stem cell sources and ethical considerations.
  • Main Results:

    • Embryonic stem cells demonstrate significant potential for generating various cell types and tissues.
    • The derivation of ESCs from human embryos remains a primary ethical concern.
    • Ongoing ethical debates impact the progression of ESC-based therapies.

    Conclusions:

    • Embryonic stem cells hold promise for future medical treatments and organ regeneration.
    • Ethical challenges must be navigated to responsibly advance the clinical application of ESCs.
    • Continued dialogue and research into ethical alternatives are crucial for the field.