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[Three cases of human fascioliasis]
Summary
Hepatic fascioliasis, a liver fluke infection, can present with fever and eosinophilia. Bithionol treatment effectively resolved symptoms in three documented cases.
Area of Science:
- Medical Parasitology
- Hepatology
- Infectious Diseases
Background:
- Hepatic fascioliasis is a parasitic liver disease caused by Fasciola hepatica.
- Diagnosis can be challenging due to non-specific symptoms and negative stool ova.
Observation:
- Three patients presented with fever, eosinophilia, and hepatomegaly.
- Diagnostic methods included intradermal testing, liver biopsy, and computed tomography (CT).
- CT revealed characteristic low-density liver lesions.
Findings:
- All patients had elevated white blood cell counts with significant eosinophilia.
- Immunoelectrophoresis confirmed Fasciola hepatica antigen, despite negative stool ova.
- Liver biopsies showed eosinophilic abscesses and Charcot-Leyden crystals.
Implications:
- Early diagnosis and treatment of hepatic fascioliasis are crucial for patient recovery.
- Bithionol demonstrated efficacy in treating hepatic fascioliasis.
- This case series highlights diagnostic challenges and successful treatment outcomes.