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Updated: Jul 11, 2026

Quantitative and Qualitative Examination of Particle-particle Interactions Using Colloidal Probe Nanoscopy
Published on: July 18, 2014
Hydrodynamic measurement of double-layer repulsion between colloidal particle and flat plate
Abstract:
Electrostatic repulsion acting across an electrolyte solution lends stability to paints and printing inks and influences cell adhesion, aggregation, and fusion. A new technique is used to measure this interaction when one of the bodies has colloidal dimensions. The potential energy profile of interactions between a 15-micrometer polystyrene sphere and a glass plate is determined by observing the distribution of separation distances (0.2 to 0.4 micrometer) that the particle samples by Brownian motion. Measurements of the speed with which the sphere is carried by linear shear flow along the wall are used to calculate separation distance. Although evidence for hydrodynamic lift is found, it is not included in the potential profile.
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