Related Experiment Video
Updated: Jul 11, 2026
06:08
Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
Published on: September 22, 2023
European position paper on rhinosinusitis and nasal polyps 2007
Wytske Fokkens1, Valerie Lund, Joaquim Mullol
1Department of Otorhinolaryngology, Amsterdam Medical Centre, P.O. box 22660, 1100 DD Amsterdam, The Netherlands. w.j.fokkens@amc.nl
Rhinology. Supplement
|September 12, 2007
Summary
Rhinosinusitis, an inflammation of the nose and sinuses, is a growing health issue. This paper provides evidence-based recommendations for diagnosing and treating rhinosinusitis and nasal polyps.
Area of Science:
- Otolaryngology
- Allergy and Immunology
- Respiratory Medicine
Background:
- Rhinosinusitis, encompassing rhinitis and sinusitis, is a prevalent and escalating health concern with substantial societal costs.
- The condition involves inflammation of the nasal passages and paranasal sinuses, impacting a significant portion of the population.
Purpose of the Study:
- To present an evidence-based position paper on rhinosinusitis and nasal polyps.
- To offer updated recommendations for diagnosis and treatment strategies.
- To identify areas for future research to advance understanding and management.
Main Methods:
- Comprehensive review of existing literature on rhinosinusitis and nasal polyps.
- Synthesis of evidence to formulate diagnostic and therapeutic guidelines.
- Analysis of epidemiological data, pathophysiology, and inflammatory mechanisms.
Main Results:
- Rhinosinusitis is defined by specific symptom clusters and diagnostic criteria, including endoscopic and CT findings.
- Evidence-based diagnostic and treatment schemes are provided for both acute and chronic forms in adults and children.
- The paper details the anatomy, pathophysiology, predisposing factors, and inflammatory pathways involved.
Conclusions:
- Effective management of rhinosinusitis and nasal polyps requires a clear understanding of diagnostic criteria and treatment options.
- The paper provides clinicians with evidence-based tools for first- and second-line management.
- Further research is needed to address the complexities and socio-economic impact of chronic rhinosinusitis and nasal polyposis.
Related Concept Videos
01:30Epistaxis
Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
01:23Chronic Pharyngitis
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
01:16Drugs Used in Upper Respiratory Disorders: Overview
Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
01:29Anatomy of Respiratory System I: Upper Respiratory Tract
The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract.
01:17Drugs Used in Lower Respiratory Disorders: Overview
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...