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Related Experiment Videos

Central pain and thalamic hyperactivity: a single photon emission computerized tomographic study.

Cesaro Pierre1, Michael W Mann, Jean Luc Moretti

  • 1Département de Neurosciences Médicales, C.H.U. Henri Mondor, 94000 Creteil France Service de Médecine Nucléaire, CHU Avicenne, 93000 Bobigny France.

Pain
|December 1, 1991
PubMed
Summary
This summary is machine-generated.

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Central post-stroke pain (CPSP) with hyperpathia may involve thalamic neuronal hyperactivity. This study used single photon emission computerized tomography (SPECT) to investigate brain activity in CPSP patients, suggesting a loss of inhibition in medial thalamic neurons.

Area of Science:

  • Neuroscience
  • Medical Imaging
  • Pain Research

Background:

  • Central post-stroke pain (CPSP) is a debilitating condition following a stroke.
  • Hyperpathia, an increased sensitivity to pain, is a challenging symptom in CPSP.
  • The underlying neurobiological mechanisms of hyperpathic CPSP remain incompletely understood.

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