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Related Experiment Video

Updated: Jul 11, 2026

Multianimal Magnetic Resonance Imaging for Tumor Measurements in Pancreatic Cancer Mouse Models

Multianimal Magnetic Resonance Imaging for Tumor Measurements in Pancreatic Cancer Mouse Models

Published on: February 3, 2026

[Gemcitabine and digestive carcinomas].

Pierre Blanchard¹, Florence Huguet, Thierry André

¹Service d'oncologie radiothérapie, Hôpital Tenon, Paris.

Bulletin Du Cancer

|September 13, 2007

Summary

This summary is machine-generated.

Gemcitabine is a well-tolerated chemotherapy drug effective against various cancers. This review details its use in pancreatic cancer and explores its potential in other digestive cancers like esophageal and liver cancer.

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Area of Science:

Oncology
Pharmacology

Context:

Gemcitabine is an approved chemotherapy for pancreatic cancer.
Its efficacy in other digestive cancers requires further investigation.

Purpose:

To review gemcitabine's infusion modalities in pancreatic cancer treatment.
To present studies on gemcitabine's use in other digestive cancers.

Summary:

Gemcitabine monotherapy, following Burris' protocol, is the standard 2006 treatment for advanced pancreatic cancer.
Phase I/II trials indicate potential activity in esophageal cancer, biliary tract adenocarcinoma, and hepatocellular carcinoma.

Impact:

This review consolidates evidence on gemcitabine's application in digestive malignancies.
It highlights the need for larger trials to confirm efficacy in non-pancreatic digestive cancers.