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Updated: Jul 11, 2026
07:35
Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray
Published on: April 25, 2014
Lack of correlation between embB mutation and ethambutol MIC in Mycobacterium tuberculosis clinical isolates from
Ruiru Shi1, Jianyuan Zhang, Koji Otomo
1Mycobacterial Reference Center, The Research Institute of Tuberculosis, 3-1-24 Matsuyama, Kiyose, Tokyo, Japan.
Antimicrobial Agents and Chemotherapy
|September 12, 2007
Abstract:
Seventy-four Mycobacterium tuberculosis clinical isolates from China were subjected to drug susceptibility testing using ethambutol, isoniazid, rifampin, and ofloxacin. The results revealed that the presence of embB mutations did not correlate with ethambutol resistance but was associated with multiple-drug resistance, especially resistance to both ethambutol and rifampin.
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