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Updated: Jul 11, 2026

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Published on: November 4, 2015

Multiple hepatic peribiliary cysts in a young pig.

M Komine¹, K Kawasako, Y Akihara

¹Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University, 582-1 Bunkyodai-Midorimachi, Ebetsu, Hokkaido 069-8501, Japan.

Veterinary Pathology

|September 12, 2007

Summary

Histopathologic examination revealed hepatic peribiliary cysts in a pig liver. These cysts, lined by mucin-producing epithelial cells, were separate from the bile duct.

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Area of Science:

Veterinary Pathology
Hepatology
Comparative Pathology

Background:

Hepatic peribiliary cysts are uncommon findings in domestic animals.
Understanding their histogenesis is crucial for differentiating them from other cystic liver lesions.

Observation:

A case study of a young, apparently healthy pig with numerous hepatic peribiliary cysts is presented.
Macroscopically, cysts containing serous fluid were distributed throughout all liver lobes.
Histopathological analysis showed cysts adjacent to large bile ducts within portal tracts.

Findings:

The cysts were lined by a single layer of columnar, cuboidal, or flattened epithelial cells, occasionally with goblet cells.
Periodic acid-Schiff/alcian blue and high-iron diamine/alcian blue staining confirmed the presence of neutral, sialo-, and sulfomucins.

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Last Updated: Jul 11, 2026

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Published on: November 4, 2015

Endocrine cells were identified in the cyst lining epithelium using Grimalius' method.

Absence of bile pigment within the cysts was confirmed by Hall's method.

Implications:

This detailed histopathologic description contributes to the understanding of hepatic peribiliary cyst formation in pigs.
The presence of mucin and endocrine cells suggests a potential origin from biliary or ductal epithelium.
This case highlights the importance of thorough histopathological evaluation for accurate diagnosis of liver cysts in animals.