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Related Concept Videos

Microtubule Associated Motor Proteins01:32

Microtubule Associated Motor Proteins

Eukaryotic cells have different motor proteins for transporting various cargo within the cell. These motor proteins differ based on the filament they associate with, the direction they move within the cell, and the type of cargo they transport. Motor proteins that associate with microtubules are known as microtubule-associated motor proteins. There are two families of microtubule-associated motor proteins —Kinesins and Dyneins. Both these proteins assist in the transport of cellular cargos...
The Movement of Organelles and Vesicles01:43

The Movement of Organelles and Vesicles

In eukaryotic cells,  cytoskeletal filaments such as actin, microtubules, and intermediate filaments form a mesh-like cytoskeletal network. These filaments serve as tracks for transporting cellular cargo. Specialized motor proteins use the chemical energy stored in adenosine triphosphate (ATP) for this transport. During interphase, microtubules are polarized, with the plus-end towards the cell periphery and the minus-end towards the cell center. Two microtubule-associated motor proteins,...
Microtubules in Cell Motility01:24

Microtubules in Cell Motility

Microtubules are thick hollow cylindrical proteins that help form the cytoskeleton. Microtubules have varied roles in the cell. These filaments help form cellular appendages like cilia and flagella, which are responsible for locomotion. The cilia arise from basal bodies, separated from the main body by a membrane-like structure forming the transition zone. This zone is the gate for the entry of lipids and proteins, creating a unique composition of lipids and proteins in the ciliary membrane and...
Microtubules in Cell Motility01:24

Microtubules in Cell Motility

Microtubules are thick hollow cylindrical proteins that help form the cytoskeleton. Microtubules have varied roles in the cell. These filaments help form cellular appendages like cilia and flagella, which are responsible for locomotion. The cilia arise from basal bodies, separated from the main body by a membrane-like structure forming the transition zone. This zone is the gate for the entry of lipids and proteins, creating a unique composition of lipids and proteins in the ciliary membrane and...
Actin Polymerization and Cell Motility01:13

Actin Polymerization and Cell Motility

Actin is a family of globular proteins that are highly abundant in eukaryotic cells. It makes up approximately 1-5% of total cell protein concentration. Actin monomers polymerize to form a complex network of polarized filaments, the actin cytoskeleton, that plays a crucial role in many cellular processes, including cell motility, division, endocytosis, and metastasis of cancer cells.
Actin cytoskeleton dynamics can produce pushing, pulling, and resistance forces that help the cell to migrate.
Mechanical Protein Functions01:58

Mechanical Protein Functions

Proteins perform many mechanical functions in a cell. These proteins can be classified into two general categories- proteins that generate mechanical forces and proteins that are subjected to mechanical forces. Proteins providing mechanical support to the structure of the cell, such as keratin, are subjected to mechanical force, whereas proteins involved in cell movement and transport of molecules across cell membranes, such as an ion pump, are examples of generating mechanical force. 

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Related Experiment Video

Updated: Jul 11, 2026

Production of Dynein and Kinesin Motor Ensembles on DNA Origami Nanostructures for Single Molecule Observation
08:09

Production of Dynein and Kinesin Motor Ensembles on DNA Origami Nanostructures for Single Molecule Observation

Published on: October 15, 2019

Cellular motors for molecular manufacturing.

C Z Dinu1, D B Chrisey, S Diez

  • 1Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany. dinuz@rpi.edu

Anatomical Record (Hoboken, N.J. : 2007)
|September 12, 2007
PubMed
Summary

This review explores microtubules and kinesin 1, essential cellular components. Their functions in cell division and organelle transport suggest potential applications for biological motors in engineered systems.

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Last Updated: Jul 11, 2026

Production of Dynein and Kinesin Motor Ensembles on DNA Origami Nanostructures for Single Molecule Observation
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Published on: October 15, 2019

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Area of Science:

  • Cell Biology
  • Biophysics
  • Biotechnology

Background:

  • Cells utilize macromolecular structures for viability and function.
  • Microtubules serve as tracks for motor proteins within cells.
  • Conventional kinesin (kinesin 1) is a key motor protein that moves along microtubules.

Purpose of the Study:

  • To review the cellular functions of kinesins, specifically conventional kinesin.
  • To explore the role of microtubules and kinesin in cellular organization and transport.
  • To consider the potential applications of biological motors in engineered environments.

Main Methods:

  • Literature review of recent research on kinesin and microtubules.
  • Analysis of cellular functions including cell division and organelle/vesicle transport.
  • Synthesis of findings to propose applications in engineered systems.

Main Results:

  • Kinesin 1 plays a critical role in organizing microtubules during cell division.
  • Kinesin 1 facilitates the movement of organelles and vesicles within the cell.
  • Understanding these motor proteins offers insights into novel organizational strategies.

Conclusions:

  • Microtubules and kinesin 1 are fundamental to cellular organization and transport.
  • The principles governing biological motors can be applied to create organized engineered systems.
  • Further research into kinesin function may lead to advancements in nanotechnology and biomaterials.