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Updated: Jul 11, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
[Metachronic thyroid metastasis secondary to renal carcinoma. Case report]
Jorge García-Olaverri Rodríguez1, Ainara Villafruela Mateo, Igor Azurmendi Arin
1Servicio de Urología, Hospital de Cruces, Baracaldo, España. jolaverri@hotmail.com
Objective:
We report the case of the patient with metachronic thyroid metastasis of a renal adenocarcinoma.
Methods:
61-year-old patient with the diagnosis of renal adenocarcinoma treated by radical nephrectomy (stage pT3bpN0M0) and subsequent interleukin-2 for twelve months presenting four years after surgery with a thyroid nodule displacing the trachea laterally, requiring left hemithyroidectomy.
Results:
Pathology reported a lesion made of clear cytoplasm tumor cells, with marked atypia and anaplastic areas, compatible with clear cell renal adenocarcinoma.
Conclusions:
Thyroid metastases are extremely rare, being renal tumors the most frequent origin. They present as painless nodules, cold in gammagram, with normal thyroid hormones. The treatment of choice is surgical excision, with a better prognosis the longer the time between the primary and the appearance of metastasis.
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