Diffuse interstitial fibrosing pneumonitis and adenovirus infection

With electron microscopy, adenovirus particles, which were almost round, variable in density, and 60-80 mmu in diameter, were observed in the nuclei of type II alveolar epithelial cells, infiltrated plasma cells and alveolar macrophages of a man with chronic interstitial fibrosing pneumonitis. The immunofluorescent technique also suggested adenovirus infection.