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Performance of abdominal ultrasonography in pediatric blunt trauma patients: a meta-analysis
James F Holmes1, Aaron Gladman, Cindy H Chang
1Department of Emergency Medicine, UC Davis School of Medicine, Davis, Sacramento, CA 95817, USA. jfholmes@ucdavis.edu
Insights
Abdominal ultrasonography (US) shows moderate accuracy in detecting intra-abdominal injuries (IAIs) in children. Its effectiveness decreases with more rigorous study analysis, suggesting it shouldn't be the sole diagnostic tool.
Area of Science:
- Pediatric Emergency Medicine
- Diagnostic Imaging
- Trauma Surgery
Background:
- Intra-abdominal injuries (IAIs) are a significant concern in pediatric blunt trauma.
- Accurate and timely diagnosis is crucial for effective management and improved outcomes.
- Abdominal ultrasonography (US) is a widely used imaging modality in evaluating these patients.
Purpose of the Study:
- To determine the optimal test performance estimates of abdominal US for identifying IAIs in children.
- To evaluate the diagnostic accuracy of abdominal US in pediatric blunt trauma patients.
Main Methods:
- A comprehensive literature search was conducted across multiple databases (MEDLINE, Embase) and other sources.
- Included prospective and retrospective studies evaluating abdominal US for detecting intraperitoneal fluid or IAIs in blunt trauma patients under 18.
- Data abstraction was performed independently by multiple authors to ensure reliability.
Main Results:
- Twenty-five articles comprising 3838 children were analyzed.
- Overall, abdominal US demonstrated a sensitivity of 80% and specificity of 96% for detecting hemoperitoneum.
- However, analysis of the most methodologically rigorous studies showed reduced test characteristics: 66% sensitivity and 95% specificity.
Conclusions:
- Abdominal US has a modest sensitivity for detecting hemoperitoneum in children, with performance declining in high-quality studies.
- A negative US result alone is insufficient to rule out IAIs.
- Hemodynamically stable children with a positive US finding require immediate abdominal computed tomographic (CT) scanning due to the high risk of IAI.
Objective:
The objective of the study was to obtain the best estimates of the test performance of abdominal ultrasonography (US) for identifying children with intraabdominal injuries (IAIs).
Methods:
We gathered studies on the use of abdominal US in injured children from the following sources: a MEDLINE and Embase search, hand searches of 5 specialty journals and 4 clinical textbooks, the bibliographies of all identified articles, and contact with experts. Both prospective and retrospective studies were included if they used abdominal US for the detection of intraperitoneal fluid or IAIs in blunt trauma patients less than 18 years of age. All authors independently abstracted data from the selected studies. Disagreements between abstractors were resolved by mutual agreement.
Results:
Twenty-five articles met the inclusion criteria, and 3838 children evaluated with abdominal US were included. Abdominal US had the following test characteristics for identifying children with hemoperitoneum: sensitivity, 80% (95% confidence interval [CI] 76%-84%); specificity, 96% (95% CI 95%-97%); positive likelihood ratio, 22.9 (95% CI 17.2-30.5); and negative likelihood ratio, 0.2 (95% CI 0.16-0.25). Using the most methodologically rigorous studies, however, yielded the following test characteristics of abdominal US for identifying children with hemoperitoneum: sensitivity, 66% (95% CI 56%-75%); specificity, 95% (95% CI 93%-97%); positive likelihood ratio, 14.5 (95% CI 9.5-22.1); and negative likelihood ratio, 0.36 (95% CI 0.27-0.47).
Conclusions:
Abdominal US has a modest sensitivity for the detection of children with hemoperitoneum; however, its test performance characteristics worsen when only the most methodologically rigorous articles are included. A negative US examination has questionable utility as the sole diagnostic test to rule out the presence of IAI. Because of the high risk of IAI, a hemodynamically stable child with a positive US examination should immediately undergo abdominal computed tomographic scanning.
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