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Updated: Jul 11, 2026
05:51
Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness
Published on: May 3, 2018
Indices of cardiovascular function derived from peripheral pulse wave analysis using radial applanation tonometry: a
Mike Crilly1, Christoph Coch, Margaret Bruce
1Department of Public Health, University of Aberdeen Medical School, Aberdeen, UK. mike.crilly@ abdn.ac.uk
Vascular Medicine (London, England)
|September 13, 2007
Summary
Pulse wave analysis (PWA) demonstrates high repeatability for cardiovascular assessment. This non-invasive technique is reliable even with inexperienced staff, suggesting its potential for routine patient care.
Area of Science:
- Cardiovascular Physiology
- Medical Diagnostics
- Biomedical Engineering
Background:
- Pulse wave analysis (PWA) is a non-invasive method to evaluate cardiovascular health.
- Key indices derived from PWA include ejection duration index (ED%), augmentation index adjusted for heart rate (AIX@75), and subendocardial viability ratio (SEVR%).
Purpose of the Study:
- To assess the within- and between-observer repeatability of PWA measurements.
- To determine the reliability of PWA for routine cardiovascular assessment in ambulant patients.
Main Methods:
- Twenty ambulant patients underwent four PWA measurements using applanation tonometry.
- Two independent nurses performed measurements using standardized equipment, blinded to each other's results.
- Bland-Altman analysis was employed to evaluate repeatability and limits of agreement.
Main Results:
- PWA measurements demonstrated high repeatability, with small mean differences and narrow limits of agreement for ED%, AIX@75, and SEVR% between observers.
- Within-observer differences were also minimal, indicating consistent measurements by individual staff.
- Results remained stable during the assessment period.
Conclusions:
- Pulse wave analysis exhibits excellent repeatability, even when performed by less experienced healthcare professionals.
- The findings support the integration of PWA into routine cardiovascular assessments for ambulant patients.
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