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Updated: Jul 11, 2026

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology
Published on: February 7, 2015
Controversies in vascular screening art versus science
1Section of Vascular Medicine, Mayo Clinic, Rochester, MN 55905, USA. rooke.thom@mayo.edu
Insights
Screening asymptomatic individuals for vascular disease is debated. Evidence-based approaches are needed, but individualized screening will likely continue due to complex issues.
Area of Science:
- Vascular Medicine
- Preventive Cardiology
- Public Health Policy
Background:
- The widespread screening of asymptomatic individuals for vascular disease presents significant medical, social, and financial challenges.
- Determining the optimal strategy for vascular screening requires careful consideration of multiple factors.
Purpose of the Study:
- To review criteria for evaluating the appropriateness of vascular screening in the general population.
- To explore key questions surrounding early detection, screening methods, target populations, and quality standards for vascular screening.
Main Methods:
- Literature review and critical analysis of existing evidence and expert opinion on vascular screening.
- Examination of the feasibility of early detection of occult vascular disease.
- Discussion of the scope and methodology of screening protocols.
Main Results:
- The effectiveness and appropriateness of vascular screening are subjects of ongoing debate.
- Key considerations include the ability to detect disease early, the choice of screening methods, and the definition of target populations.
- Establishing universal screening standards faces challenges due to the complexity and heterogeneity of vascular diseases.
Conclusions:
- While evidence-based approaches can resolve some screening controversies, many issues lack definitive scientific solutions.
- Individualized patient assessment and tailored screening strategies are essential for the foreseeable future.
- A balanced approach considering clinical evidence and patient-specific factors is crucial for vascular screening decisions.
Abstract:
Whether or not to screen asymptomatic members of the general public for various forms of vascular disease is a controversial issue with huge medical, social, and financial ramifications. This article reviews several criteria for determining the appropriateness of vascular screening, including: (1) is it possible to detect occult vascular disease ;early'?; (2) what should we screen for, and how should we do it?; (3) who should be screened?; and (4) what standards for vascular screening should be set? While some of these controversies may ultimately be resolvable using an evidence-based approach, it is apparent that there are issues which will not be amenable to strict scientific analysis. Individualized approaches to screening will therefore remain the rule for the foreseeable future.
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