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Related Concept Videos

Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and the...
Dosage Regimens: Partial Pharmacokinetic Parameters01:01

Dosage Regimens: Partial Pharmacokinetic Parameters

It is not uncommon for complete drug pharmacokinetic profiles to remain elusive in pharmacokinetics. This necessitates certain educated assumptions by pharmacokineticists to determine appropriate dosage regimens without comprehensive pharmacokinetic data from animal or human studies. One prevalent assumption is setting the bioavailability factor, denoted as F, to 1 or 100%. This assumption caters to the scenario where a drug doesn't achieve full systemic absorption, resulting in the patient...
Drug Dosing in Renal Diseases: Dose Adjustments Based on Drug Clearance and Elimination Rate Constant01:25

Drug Dosing in Renal Diseases: Dose Adjustments Based on Drug Clearance and Elimination Rate Constant

In patients with renal disease, dosage adjustments are necessary to maintain therapeutic plasma drug concentrations and prevent toxicity or subtherapeutic exposure. Renal impairment alters drug pharmacokinetics, especially in conditions like uremia, where changes such as prolonged elimination half-life and altered apparent volume of distribution can significantly affect drug disposition. These changes require careful modification of the dosing regimen to achieve the desired clinical...
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...

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Updated: Jul 11, 2026

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy (PRRT): 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
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Patient dose from CT: a literature review.

John E Colang1, Jeff B Killion, Eliseo Vano

  • 1Intel Corporation, Albuquerque, New Mexico, USA.

Radiologic Technology
|September 13, 2007
PubMed
Summary

Tracking cumulative radiation dose from computed tomography (CT) and other imaging exams is crucial. Current research explores methods for dose reduction and lifetime exposure tracking, but uniform protocols are needed.

Area of Science:

  • Medical Imaging
  • Radiology
  • Radiation Safety

Background:

  • Computed tomography (CT) examinations are increasingly prevalent.
  • CT scans contribute significantly to cumulative patient radiation exposure.
  • Managing medical radiation exposure is a growing public health concern.

Purpose of the Study:

  • To investigate patient radiation dose issues in medical imaging.
  • To explore methods for minimizing radiation dose during CT and other imaging procedures.
  • To assess the feasibility of tracking lifetime medical radiation exposure.

Main Methods:

  • A comprehensive review of recent scientific literature was performed.
  • Current knowledge on patient radiation dose levels was evaluated.

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  • Protocols for dose reduction and systems for cumulative dose tracking were assessed.

    • Main Results:

    • There are currently no established regulations for tracking cumulative patient radiation dose.
    • Potential methods for recording, tracking, and storing dose data were discussed.
    • Standardizing dose data in DICOM headers and electronic health records were proposed solutions.

    Conclusions:

    • Further research is essential for developing and implementing standardized dose tracking procedures.
    • Uniform protocols for minimizing patient radiation dose require further development.
    • Effective systems for tracking cumulative radiation exposure are needed.