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External mechanical compression reduces regional arterial stiffness.

Kevin S Heffernan1, David G Edwards, Lindy Rossow

  • 1The Exercise and Cardiovascular Research Laboratory, Department of Kinesiology and Community Health, Rehabilitation Education Center, University of Illinois at Urbana-Champaign, 1207 S. Oak St, Champaign, IL 61820, USA. kheffer2@uiuc.edu

European Journal of Applied Physiology
|September 13, 2007
PubMed
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External mechanical compression reduced local artery stiffness in the compressed limb. This study investigated if localized compression mimics exercise effects on vascular stiffness.

Area of Science:

  • Physiology
  • Vascular Biology
  • Exercise Science

Background:

  • Exercise, particularly resistance training, reduces local arterial stiffness in the exercised limb.
  • The mechanism may involve mechanical compression of vasculature during exercise.
  • This study explores localized external compression as a model to understand these effects.

Purpose of the Study:

  • To investigate the effects of externally applied mechanical compression on arterial stiffness.
  • To determine if localized compression mimics exercise-induced changes in vascular stiffness.

Main Methods:

  • 18 healthy young adults underwent localized supra-systolic pressure cuff inflation/deflation cycles on one leg.
  • Pulse wave velocity (PWV) measured central (carotid-femoral) and peripheral (femoral-dorsalis pedis) arterial stiffness before and after compression.

Related Experiment Videos

  • A control leg and central measures were used for comparison.

    • Main Results:

    • No significant changes in central arterial stiffness (carotid-femoral PWV).
    • No significant changes in peripheral arterial stiffness of the non-compressed leg.
    • Significant reduction in peripheral arterial stiffness of the compressed leg post-intervention.

    Conclusions:

    • Localized external mechanical compression can reduce arterial stiffness in the compressed limb.
    • This finding supports the hypothesis that mechanical compression is a key factor in exercise-induced reductions in local vascular stiffness.
    • External compression offers a potential non-exercise method to modulate local vascular health.