Successful treatment with rituximab in a patient with an acquired factor V inhibitor

Agnes Lebrun1, Catherine Leroy-Matheron, Jean-Benoit Arlet

  • 1Department of Internal Medicine, Henri Mondor University Hospital, Assistance Publique-Hôpitaux de Paris, Créteil, France.

Rituximab has already been successfully used to treat immune-mediated bleeding disorders such as acquired factor VIII inhibitor. We report here a case of severe acquired factor V (FV) inhibitor deficiency due to FV inhibitor which has been dramatically improved after rituximab.