Related Experiment Video
Updated: Jul 11, 2026

Establishing a Competing Risk Regression Nomogram Model for Survival Data
Published on: October 23, 2020
Does age affect the prognosis of patients with testicular germ cell tumor?
Kubilay Inci1, Hasan Serkan Dogan, Bulent Akdogan
1Department of Urology, Hacettepe University, Faculty of Medicine, Ankara, Turkey.
Introduction:
In this study, the effect of age on the prognosis of testicular germ cell tumors in patients over 40 was investigated.
Materials And Methods:
Ninety-three patients with testicular germ cell tumor who were 40 years old and over were identified in our germ cell tumor database. Patients were grouped according to their age with those between 40 and 44, 45 and 49 and 50 and over constituting groups I, II and III, respectively.
Results:
Only 15% of the patients of group III had localized disease (p = 0.002). Group III patients had a significantly lower response rate to initial chemotherapy and a higher disease progression rate during therapy (complete response rate: 33.3%, progression rate: 44.4%, p = 0.035). The multivariate analysis revealed that advanced stage was the only independent prognostic factor for survival (p = 0.0011).
Conclusion:
Testicular germ cell tumor patients over 50 years old presented with a more advanced stage and had higher disease progression and disease mortality rates.
Related Concept Videos
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Pharmacodynamics in Geriatric Patients: Effects of Age
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism
