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Updated: Jul 11, 2026

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification
07:32

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Published on: April 7, 2017

Enzyme-based antifouling coatings: a review.

S M Olsen1, L T Pedersen, M H Laursen

  • 1Hempel A/S, Denmark.

Biofouling
|September 14, 2007
PubMed
Summary

Enzymatic antifouling (AF) coatings offer innovative protection for underwater structures. While direct enzymatic AF has seen commercialization, challenges remain in achieving broad-spectrum efficacy, and indirect methods face substrate supply and regulatory hurdles.

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Area of Science:

  • Marine biology
  • Biotechnology
  • Materials science

Background:

  • Underwater structures face significant biofouling challenges, impacting performance and maintenance.
  • Enzymatic antifouling (AF) offers a promising, potentially eco-friendly alternative to traditional methods.
  • Current literature on enzymatic AF technologies requires systematic review to assess progress and identify barriers.

Purpose of the Study:

  • To systematically review the literature on enzymatic antifouling (AF) protection for underwater structures.
  • To evaluate the current state of enzymatic AF technology, including direct and indirect approaches.
  • To identify key obstacles hindering the successful development and commercialization of enzymatic AF coatings.

Main Methods:

  • Systematic literature review of scientific publications and patents.
  • Categorization of enzymatic AF approaches into direct and indirect methods.
  • Analysis of technological limitations, including enzyme efficacy, substrate supply, and regulatory aspects.

Main Results:

  • Direct enzymatic AF has led to patented technologies and one commercial product, but broad-spectrum efficacy is not yet achieved.
  • Indirect enzymatic AF, where enzymes release biocides, is not commercially available.
  • Key limitations for indirect AF include unstable substrate supply and unresolved legislative questions regarding biocidal classification of enzyme systems.

Conclusions:

  • Enzymatic antifouling presents a developing field with notable progress in direct applications.
  • Significant challenges persist in achieving broad-spectrum efficacy and overcoming substrate supply and regulatory issues, particularly for indirect enzymatic AF.
  • Further research and development are needed to overcome these obstacles for widespread adoption of enzymatic AF coatings.